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（生理或智力上的）殘障，殘疾
A handicap is a physical or mental disability.
例句
He lost his leg when he was ten, but learnt to overcome his handicap.
他10歲時失去了一條腿，但他學會了克服自己的殘疾。
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不利條件;障礙
A handicap is an event or situation that places you at a disadvantage and makes it harder for you to do something.
例句
She was away from school for 15 weeks, a handicap she could have done without...
她有15周沒上學，這給她帶來了本不該有的障礙。
Being a foreigner was not a handicap.
身為外國人并不是一個障礙。
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VERB
妨礙;使不利
If an event or a situation handicaps someone or something, it places them at a disadvantage.
例句
Greater levels of stress may seriously handicap some students...
壓力的加重可能會給一些學生帶來嚴重的負面影響。
The industrial injuries scheme takes into account the actual disability and whether it handicaps a person in working.
工傷賠償方案要考慮實際殘疾情況以及殘疾是否會影響其工作能力。
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（高爾夫運動中的）給弱者增加的桿數，差點
In golf, a handicap is an advantage given to someone who is not a good player, in order to make the players more equal. As you improve, your handicap gets lower.
例句
I see your handicap is down from 16 to 12.
我發現你的差點已從16桿降到了12桿。
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（賽馬比賽的）讓步賽
In horse racing, a handicap is a race in which some competitors are given a disadvantage of extra weight in an attempt to give everyone an equal chance of winning.